Capacity to Provide Informed Consent among Adults with Bipolar Disorder
Bipolar disorder is a major psychiatric disorder that is defined by the occurrence of mania that typically also experiences episodes of depression (Fountoulakis et al, 2007). In the United States, the lifetime prevalence estimate of bipolar I disorder is 1.1% (Kleinman et al, 2003), with an estimated annual cost of $45 billion (Merikangas et al, 2007). Several studies have noted episode-related decrements in cognitive function (Denicoff et al, 1999), which may affect the ability of these patients to provide informed consent to participate in research.
Source: Journal of Affective Disorders - Category: Neurology Authors: Christina C. Klein, Michelle B. Jolson, Meg Lazarus, Brian Masterson, Thomas J. Blom, Caleb M. Adler, Melissa P. DelBello, Stephen M. Strakowski Source Type: research