Pirfenidone increases the epithelialization rate of skin graft donor sites

Skin grafting is one of the oldest and most common procedures in plastic surgery, and the treatment of skin donor sites has been an important issue for decades [1]. Split thickness skin grafts (STSGs) contain the entirety of the epidermis and a variable amount of dermis depending on the thickness of the harvested graft [2]. This procedure creates a wound in the donor site that is similar to a superficial, second-degree burn, which usually takes between 14 and 21days to spontaneously heal with relatively inconspicuous scarring [3].
Source: Burns : Journal of the International Society for Burn Injuries - Category: Cosmetic Surgery Authors: Source Type: research