Quantity fluctuations of illicitly used opioids and overdose risk

Reduced opioid tolerance is believed to be associated with overdose risk, although this relationship has primarily been examined in the context of gaps and frequency of opioid use. We sought to assess how changes in the quantity of opioids used, as opposed to periods of abstinence or overall frequency of use, relate to overdose risk.

Source: International Journal of Drug Policy - May 26, 2018 Category: Addiction Authors: Christopher Rowe, Eliza Wheeler, Eric Vittinghoff, Glenn-Milo Santos, Emily Behar, Phillip O. Coffin Tags: Research Paper Source Type: research