The effectiveness of Cytisine versus Nicotine Replacement Treatment for smoking cessation in the Russian Federation

Cytisine is a plant-based alkaloid (Webb, 1980; Godley, 2006) that has been marketed as a smoking cessation medication (both with and without a prescription) for more than 50 years in 17 countries within Central and Eastern Europe (Tutka& Zato ński, 2006). Like varenicline, cytisine is a partial agonist of nicotinic acetylcholine receptors (nAChRs) with an affinity for the α4β2 receptor subtype (Coe et al., 2005). However, cytisine differs from varenicline in its pharmacokinetics, cost, and treatment period (Etter, Lukas, Benowitz, Wes t,& Dresler, 2008).
Source: International Journal of Drug Policy - Category: Addiction Authors: Tags: Short Report Source Type: research