Risk score system for the prediction of hepatocellular carcinoma in patients with type 2 diabetes: Taiwan Diabetes Study

This study aims to develop a risk score system for hepatocellular carcinoma (HCC) in patients with type 2 diabetes using the Taiwan National Diabetes Care Management Program (NDCMP) database. This retrospective cohort study included 31,723 Chinese patients who had type 2 diabetes, aged 30 –84 years. Participants were randomly grouped into derivation and validation sets in 2:1 ratio. Cox proportional hazard regression models were used to identify the risk factors of HCC in the derivation set. Discrimination ability of the model was assessed by means of a receiver operating character istic curve and performance was expressed as the c statistic, assessed internally on validation data sets.

Source: Seminars in Oncology - August 7, 2018 Category: Cancer & Oncology Authors: Tsai-Chung Li, Chia-Ing Li, Chiu-Shong Liu, Wen-Yuan Lin, Chih-Hsueh Lin, Sing-Yu Yang, Cheng-Chieh Lin Source Type: research