Diminished modulation of motor cortical reactivity during context-based action observation in schizophrenia

Deficient mirror neuron system (MNS)-activity is associated with social cognition deficits in schizophrenia. However, it is not known how socio-emotional contexts modulate the MNS-response. In a Transcranial Magnetic Stimulation (TMS)-experiment, we aimed to compare putative MNS-responses to action observation stimuli with and without a context, in patients with schizophrenia and healthy subjects.

Source: Schizophrenia Research - August 7, 2018 Category: Psychiatry Authors: Virupakshappa Irappa Bagewadi, Urvakhsh Meherwan Mehta, Shalini S. Naik, Ramajayam Govindaraj, Shivarama Varambally, Shyam Sundar Arumugham, C. Naveen Kumar, Jagadisha Thirthalli Source Type: research