Activity of a nitric oxide-generating wound treatment system against wound pathogen biofilms

The microbial burden of acute and chronic wounds plays an important role in impaired healing and development of infection-related complications. Prevalence of infection in chronic wounds is reported as 53% [1]. Inadequate infection management of chronic wounds can result in lower limb amputation and bloodstream invasion, and complications, such as sepsis, multi-organ failure and death [2]. Biofilm formation is now thought to exacerbate wound infection and delay healing in chronic wounds and following acute injury [3 –5].
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Source Type: research