Discriminating Power of Rapidly Mutating Y-STRs in deep rooted endogamous pedigrees from Sindhi population of Pakistan

Y chromosome is widely used in human population study[1], paternity testing, investigation of sexual offences, and missing persons[2], because it shows male inheritance and substantial structuring in human populations[3]. For these applications, the currently available Y-STR panels (AmpF ℓSTR® Yfiler™ kit& PowerPlex ® Y23 System) have proven to be effective tools with numerous case reports. Without any doubt, currently used Y-STR markers are very potential for the reconstruction of human population history[4–6], including estimation of demographic parameters[7], as well as for genealogical relationships[8– 10] and male lineage determination in forensic applications[11–13].
Source: Legal Medicine - Category: Forensic Medicine Authors: Source Type: research