Novel MprA binding motifs in the phoP regulatory region in Mycobacterium tuberculosis

In this study, we found that the response regulator MprA can bind to the phoP promoter. Four repeat motifs, D1-D4, constituting two predicted binding sites, were located in the region protected by MprA in DNA footprinting.

Source: Tuberculosis - August 3, 2018 Category: Respiratory Medicine Authors: Peipei Zhang, Jiafang Fu, Gongli Zong, Meng Liu, Xiuhua Pang, Guangxiang Cao Tags: Molecular Aspects Source Type: research