Quantification of the detailed cardiac left ventricular trabecular morphogenesis in the mouse embryo

The development of the myocardium appears to be similar in many vertebrates. In particular, before the intramural cardiac vessels appear, the ventricular walls consist mainly of trabeculations. Those early trabeculations increase myocardial surface area and serve to increase myocardial oxygenation and nutrient delivery by diffusion, while sufficient tissue volume builds up for myocardium development at the later stages. However, the decrease in trabecular complexity does not lead to a disappearance of the trabeculations.

Source: Medical Image Analysis - August 2, 2018 Category: Radiology Authors: Bruno Paun, Bart Bijnens, Andrew C. Cook, Timothy J. Mohun, Constantine Butakoff Source Type: research