Differential engagement of cognitive control regions and subgenual cingulate based upon presence or absence of comorbid anxiety with depression

Deficits in cognitive control are a potential mechanism underlying impaired emotion regulation in mood disorders (Langenecker et  al. 2014; Langenecker et al., under review; Phillips et al. 2003). Major Depressive Disorder (MDD) is consistently associated with cognitive deficits, including in executive function, working memory and attention (Bora, Harrison et al. 2013; Jenkins et al. 2016; McIntyre et al., 2013; Snyder, 2013). Anxiety Disorders (AD) are also associated with cognitive deficits, although to a lesser extent (Castaneda et al.

Source: Journal of Affective Disorders - August 1, 2018 Category: Neurology Authors: Lisanne M. Jenkins, Jonathan P. Stange, Katie L. Bessette, Yi-Shin Chang, Samantha D. Corwin, Kristy A. Skerrett, V íctor G. Patrón, Jon-Kar Zubieta, Natania A. Crane, Alessandra M. Passarotti, Daniel S. Pine, Scott A. Langenecker Tags: Research paper Source Type: research