Bone metabolism in pediatric burned patients: A review

Severe burns in children can cause growth delays, bone loss, and wasting of lean body mass and muscle [1 –3]. The risk of fractures is increased after burn, particularly because of the reduced bone mass and possibly secondary to a slow growth velocity [4,5]. This effect can be attributed to the significant increase in endogenous glucocorticoid secretion and the increase in proinflammatory cytokine pr oduction [6]. Additionally, bone mass decrease may also be attributed to hypoparathyroidism and calcium wasting, as well as a consistent vitamin D deficiency [4,7–12].
Source: Burns : Journal of the International Society for Burn Injuries - Category: Cosmetic Surgery Authors: Tags: Review Source Type: research