Effect of fronto-temporal transcranial direct current stimulation on corollary discharge in schizophrenia: A randomized, double-blind, sham-controlled mediation analysis study

Deficient corollary discharge (CD) has been linked to agency related anomalies in schizophrenia (SCZ) (Poletti et al., 2017), especially with pathophysiology of auditory verbal hallucination (AVH) (Heinks-Maldonado et al., 2007). Transcranial Direct Current Stimulation (tDCS), a non-invasive, safe neuromodulation technique, is a re-emerging intervention (Brunoni et al., 2012) with promising potential to treat schizophrenia (Mondino et al., 2015a). In an open label study, we reported add-on tDCS to ameliorate CD deficit in SCZ patients with persistent AVH (Nawani et al., 2014).
Source: Schizophrenia Research - Category: Psychiatry Authors: Tags: Letter to the Editor Source Type: research