Geometric and Mechanical Bone Response to a Multidisciplinary Weight Loss Intervention in Adolescents With Obesity: The ADIBOX Study

The effectiveness of structured multidisciplinary weight loss (WL) programs combining nutrition and physical activity on bone geometry and strength remains uncertain in adolescents with obesity. The study investigated the impact of a structured WL intervention on bone geometry and strength in adolescents with obesity. Thirty-one adolescents with obesity (mean [standard deviation] 13.61 [1.27] yr, body mass index Z-score 2.26 [0.30]) experienced an 8-mo WL program. A group of 23 maturation-matched controls (mean [standard deviation] 15.90 [0.43] yr, body mass index Z-score −0.12 [0.48]) were recruited for calculating Z-scores.

Source: Journal of Clinical Densitometry - August 1, 2018 Category: Radiology Authors: Elodie Chaplais, Geraldine Naughton, Frederic Dutheil, Julie Masurier, David Greene, Bruno Pereira, Martine Duclos, David Thivel, Daniel Courteix Source Type: research