Can Liver and Diet Impact Alzheimer's Risk?

This research has a variety of interesting implications. For example, it highlights a potential relationship between conditions such as obesity and diabetes and Alzheimer ’s.ByAlzheimer's Reading RoomReduced levels of plasmalogens — a class of lipids created in the liver that are integral to cell membranes in the brain—are associated with an increased risk of Alzheimer ’s Disease, according to new research.Plasmalogens are created in the liver and are dispersed through the blood stream in the form of lipoproteins, which also transport cholesterol and other lipids to and from cells and tissues throughout the body, including the brain.How to Test Your Memory for Alzheimer's and Dementia (5 Best Tests)Subscribe to the Alzheimer's Reading RoomEmail:Mitchel A. Kling, and the multi-institutional Alzheimer ’s Disease Metabolomics Consortium led by Rima F. Kaddurah-Daouk, PhD, at Duke University School of Medicine, developed three indices for measuring the amount of these lipids related to cognition, in order to identify whether reduced levels in the bloodstream are associatedwith an increased risk of Alzheimer ’s disease, mild cognitive impairment (MCI), overall cognitive function, and/or other biomarkers of neurodegeneration in Alzheimer’s disease.The three indices measured: the ratios of plasmalogens to each other; the ratios of plasmalogens to their closely-related, more conventional lipid counterparts; and a combination of these two quantities.They measured several...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: alzheimer's risk alzheimers research diabetes diet health lifestyle liver obesity science Source Type: blogs