Functional variants at the 21q22.3 locus involved in breast cancer progression identified by screening of genome-wide estrogen response elements

Conclusion:
These findings support the idea that functional variants in the ER?-regulating sequence at 21q22.3 is important in determining breast cancer progression.

Source: Breast Cancer Research - October 9, 2014 Category: Cancer & Oncology Authors: Chia-Ni HsiungHou-Wei ChuYuan-Ling HuangWen-Cheng ChouLing-Yueh HuHuan-Ming HsuPei-Ei WuMing-Feng HouJyh-Cherng YuChen-Yang Shen Source Type: research