An immediate, single intravesical instillation of mitomycin C is of benefit in patients with non –muscle-invasive bladder cancer irrespective of prognostic risk groups

The treatment of non –muscle-invasive bladder cancer (NMIBC) remains a challenge because of its tendency to recur and progress [1,2]. To decrease the risk of recurrence, an immediate instillation of chemotherapy after transurethral resection (TURBT) is administered. The instillation prevents recurrence through eradica tion of floating tumor cells and residual tumor at the tumor site and by eradication of small overlooked synchronous tumors [3,4]. A recent systematic review and individual patient data meta-analysis by Sylvester et al.

Source: Urologic Oncology: Seminars and Original Investigations - July 29, 2018 Category: Urology & Nephrology Authors: Judith Bosschieter, Jakko A. Nieuwenhuijzen, Andr é N. Vis, Tessa van Ginkel, Birgit I. Lissenberg-Witte, Goedele M.A. Beckers, R. Jeroen A. van Moorselaar Tags: Original article Source Type: research