Predicting Gleason Group Progression for Men on Prostate Cancer Active Surveillance: The Role of a Negative Confirmatory MRI-US Fusion Biopsy

Active surveillance (AS) has gained acceptance as an alternative to definitive therapy for many men with prostate cancer (PCa). Confirmatory biopsies to assess the appropriateness of AS are routinely performed and negative biopsies are regarded as a favorable prognostic indicator. Our study sought to determine the prognostic implications of negative multi-parametric magnetic resonance imaging (mpMRI)-transrectal ultrasound (TRUS) guided fusion biopsy (FB) consisting of extended sextant, systematic biopsy (SB) plus mpMRI-guided targeted biopsy of suspicious MRI lesions.

Source: The Journal of Urology - July 28, 2018 Category: Urology & Nephrology Authors: Jonathan B. Bloom, Graham Hale, Samuel A. Gold, Kareem Rayn, Clayton Smith, Sherif Mehralivand, Marcin Czarniecki, Vladimir Valera, Bradford J. Wood, Maria Merino, Peter L. Choyke, Howard L. Parnes, Baris Turkbey, Peter A. Pinto Source Type: research