Cellular DNA quantification in respiratory samples for the normalization of viral load: a real need?

Respiratory tract infections (RTI) have an enormous social and economic impact, with a high incidence of hospitalization and high public health care costs [1]. Because of similar clinical symptoms and simultaneous circulation of several different viruses, their etiology is often difficult to determine. Adequate specimen collection is the first crucial step for the correct diagnosis of influenza and other respiratory infections. Dilution correction in nasopharyngeal aspirates might improve the detection of respiratory infections [2].

Source: Journal of Clinical Virology - July 27, 2018 Category: Virology Authors: Antonio Piralla, Federica Giardina, Francesca Rovida, Giulia Campanini, Fausto Baldanti Source Type: research