Epicardial Adipose Tissue feeding and overfeeding the Heart

Epicardial adipose tissue is a peculiar visceral fat depot with unique anatomical, biomolecular and genetic features. Epicardial fat displays both physiological and pathological properties. Epicardial fat expresses genes and secretes cytokines actively involved in the thermogenesis and regulation of lipid and glucose metabolism of the adjacent myocardium. A disequilibrium between epicardial fat feeding and overfeeding the myocardium with free fatty acids leads to intra-myocardial fat infiltration causing organ damages and clinical consequences.
Source: Nutrition - Category: Nutrition Authors: Tags: Review Source Type: research