GEORCC Recommendations on Target Volumes in radiotherapy for Head Neck Cancer of Unkown Primary

Cancer of unknown primary site (CUP) includes a group of metastatic tumors in which, after a thorough staging evaluation, the primary origin is not identified (Jesse et al., 1973). A specific category within CUP is that of metastatic cervical lymph node of unknown primary, or Head Neck Cancer of Unknown Primary (HNCUP). This group is less than 10% of head and neck cancer whereas its most frequent histological diagnosis is squamous cell carcinoma (50-70%) (Strojan et al., 2013). After treatment a small percentage of patients will develop a subsequent mucosal primary (SMP) (Nieder et al., 2001) tumor.

Source: Critical Reviews in Oncology Hematology - July 24, 2018 Category: Cancer & Oncology Authors: Joaqu ín Cabrera Rodríguez, Jon Cacicedo, Jordi Giralt, Enrique García Miragall, Marta Lloret, Fernando Arias, María Angeles González Ruiz, Jorge Contreras Source Type: research