Is there a symptomatic distinction between the affective psychoses and schizophrenia? A machine learning approach

Dubiety exists over whether clinical symptoms of schizophrenia can be distinguished from affective psychosis, the assumption being that absence of a “point of rarity” indicates lack of nosological distinction, based on prior group-level analyses. Advanced machine learning techniques, using unsupervised (hierarchical clustering) and supervised (regularized logistic regression algorithm and nested-cross-validation) were applied to a dataset of 202 patients with functional psychosis (schizophrenia n = 120, affective psychosis, n = 82).

Source: Schizophrenia Research - July 24, 2018 Category: Psychiatry Authors: S. Jauhar, R. Krishnadas, M.M. Nour, D. Cunningham-Owens, E.C. Johnstone, S.M. Lawrie Source Type: research