Neutral Sphingomyelinase-2 is a Redox Sensitive Enzyme:Role of Catalytic Cysteine Residues in Regulation of Enzymatic Activity through Changes in Oligomeric State

In conclusion, our results identify nSMase-2 as a redox-sensitive enzyme, whose basal activity is influenced by thioredoxin-mediated changes in its oligomeric state.

Source: BJ Signal - October 7, 2014 Category: Biochemistry Authors: P Patrick Dotson II, A A. Karakashian, M N. Nikolova-Karakashian Tags: BJ Biomolecules Source Type: research