Problematic eating behaviours, changes in appetite, and weight gain in Major Depressive Disorder: The role of leptin

The global prevalence of Major Depressive Disorder (MDD) is rising annually, with this rise currently being attributed to increasing stress, endocrine dysfunction, modern lifestyle characteristics and dietary patterns (Hidaka, 2012). Altered eating behaviours, and appetite and weight dysregulation, are central diagnostic criteria of MDD (American Psychiatric Association, 2013). MDD is a risk factor for obesity, cardiovascular disease and metabolic syndrome (Cassano& Fava, 2002; Penninx et al., 2013), with a key risk factor being increased appetite; which can occur in MDD (American Psychiatric Association, 2013).

Source: Journal of Affective Disorders - July 23, 2018 Category: Neurology Authors: Jessica G. Mills, Susan J. Thomas, Theresa A. Larkin, Nagesh B. Pai, Chao Deng Tags: Research paper Source Type: research