Impact of Comprehensive Treatment for First Episode Psychosis on Substance Use Outcomes: A Randomized Controlled Trial

Lifetime co-occurring substance use disorders are common at the time of presentation for treatment of a first episode of primary psychosis and persistent substance use disorder (SUD) leads to poorer outcomes. We assessed whether the NAVIGATE program, a coordinated specialty care service that includes optional substance abuse content reduced substance use compared to usual care in 404 individuals in the Recovery After Initial Schizophrenia Episode-Early Treatment Program (RAISE-ETP) study. Participants were randomized to two years of NAVIGATE (n  = 223) or usual care (n = 181) and assessed monthly for substance use.

Source: Psychiatry Research - July 23, 2018 Category: Psychiatry Authors: Corinne Cather, Mary F. Brunette, Kim T. Mueser, Steven F. Babbin, Robert Rosenheck, Christoph U. Correll, Piper Kalos-Meyer Source Type: research