Early life stress accelerates age-induced effects on neurogenesis, depression, and metabolic risk

Metabolic syndrome (MetS) is a cluster of risk factors that include obesity, insulin resistance, hyperlipidemia, and hypertension. MetS increases the risk for cardiovascular disease and type 2 diabetes (T2DM), and shows a high comorbidity with depression (Zanoveli et al., 2016). However, this relationship is complex and poorly understood. Clinical evidence has shown that while T2DM did not predict symptoms of depression or anxiety, these symptoms emerged as significant risk factors for the onset of T2DM.

Source: Psychoneuroendocrinology - July 18, 2018 Category: Psychiatry Authors: Roberto Ruiz, Ang élica Roque, Edel Pineda, Paula Licona-Limón, Juan José Valdéz-Alarcón, Naima Lajud Source Type: research