Sedative, Analgesic and Behavioral Effects of Nalbuphine-Xylazine and Nalbuphine-Midazolam Combinations in Dogs

The purpose of the present study was to evaluate the sedative, analgesic and behavioral effects of nalbuphine-xylazine (NX) and nalbuphine-midazolam (NM) combinations for neuroleptanalgesia in dogs. A prospective randomized cross-over study was done on six adult mongrel dogs. Dogs were randomly allocated into NX and NM groups with a washout period 2 weeks. Nalbuphine was given at dose of 0.5 mg / kg IV approximately 20 minutes before administration of the tranquilizer. Dogs were randomly allocated into one of the two groups: NX group received xylazine at a dose of 1mg / kg IV; and NM group received midazolam at a dose of 0.5 mg / kg IV.
Source: Journal of Veterinary Behavior: Clinical Applications and Research - Category: Veterinary Research Authors: Source Type: research