Role of complement system in patients with biopsy-proven IgG4 related kidney disease

Hypocomplementaemia has been frequently reported in IgG4 related kidney disease (IgG4-RKD). However, studies on the role of complement system in IgG4-RKD are lacking. A total of 40429 renal biopsies from January 2010 to January 2018 were re-examined in the present study, and 17 patients were confirmed to meet the criteria of IgG4-RKD. According to the serum C3 levels, they were divided into two groups: the low C3 group (C3

Source: Human Pathology - July 18, 2018 Category: Pathology Authors: Rong Wang, Dafeng He, Lili Zhao, Shaoshan Liang, Dandan Liang, Feng Xu, Mingchao Zhang, Xiaodong Zhu, Huiping Chen, Honglang Xie, Caihong Zeng, Zheng Tang, Zhihong Liu Tags: Original Contributions Source Type: research