Therapeutic effect of Imiquimod enhanced ALA-PDT on cutaneous squamous cell carcinoma

Cutaneous squamous cell carcinoma (cSCC) is an increasingly common diagnosis worldwide. It has an estimated annual incidence of 700,000 in United States [1]. Treatment of majority of cSCC lesions is effectively accomplished by surgical excision [2]. But excision of large lesions, multiple lesions, or lesions in surgically difficult areas, such as the face, distal extremities and genitals, often causes functional loss or cosmetic disfigurement. Moreover, some patients are not eligible for surgery because of their poor general health and concomitant use of anticoagulant or immunosuppressive drugs [3].

Source: Photodiagnosis and Photodynamic Therapy - July 17, 2018 Category: Laser Surgery Authors: Anil Kumar Bhatta, Peiru Wang, Uma Keyal, Zijun Zhao, Jie Ji, Lude Zhu, Xiuli Wang, Guolong Zhang Source Type: research