Thresholds for severity, remission and recovery using the functioning assessment short test (fast) in bipolar disorder

Randomized controlled trials (RCTs) in psychiatry rely on clinician-rated instruments to study the treatment efficacy. Traditionally, the outcomes in RCTs have been defined in a context of reduction of symptoms (response/partial response/non response). However, in the last years, the focus has also moved from clinical remission to functional recovery (Vieta  and Torrent, 2016). Hence, the most meaningful endpoint is no longer mere improvement, nor remission, but recovery. Indeed, functional recovery is, for some patients, a difficult goal, even if they have reached clinical remission.

Source: Journal of Affective Disorders - July 16, 2018 Category: Neurology Authors: C.M. Bonn ín, A. Martínez-Arán, M. Reinares, M. Valentí, B. Solé, E. Jiménez, L. Montejo, E. Vieta, A.R. Rosa Source Type: research