Cytokines in cerebrospinal fluid of patients with schizophrenia spectrum disorders: New data and an updated meta-analysis
Few studies have been conducted examining cytokines in cerebrospinal fluid of patients compared to healthy volunteers. The goals of this study were: 1) to report original data detailing cytokine levels in the cerebrospinal fluid (CSF) of 10 patients with a schizophrenia spectrum disorder (SSD) diagnosis and 10 healthy controls and 2) to conduct a meta-analysis of the available data on cytokine levels in the CSF of patients with SSD compared to healthy controls, including our new data. Cytokine concentrations were measured using the Q-plex Human Cytokine Screen array in CSF of 10 patients with SSD and 10 healthy volunteers.
Source: Schizophrenia Research - Category: Psychiatry Authors: Juan A. Gallego, Emily A. Blanco, Sehba Husain-Krautter, E. Madeline Fagen, Paula Moreno-Merino, Juan A. del Ojo-Jim énez, Anthony Ahmed, Thomas L. Rothstein, Todd Lencz, Anil K. Malhotra Source Type: research