Unravelling mechanisms of nitrofurantoin resistance and epidemiological characteristics among Escherichia coli clinical isolates

Escherichia coli is one of the most common Gram-negative bacterial pathogens causing uncomplicated urinary tract infections (UTIs) and opportunistic infections in immunocompromised hosts both in hospital and community settings [1,2]. Recently, the rate of multidrug-resistant E. coli clinical isolates has shown an increasing trend, bringing greater attention and distress to clinicians and infectious diseases practitioners [3,4]. In addition, the lack of effective clinical treatments against multidrug-resistant E.
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Source Type: research