Preventive medicine of von Hippel-Lindau disease-associated pancreatic neuroendocrine tumors

This study demonstrates that patients with PanNET approaching the cut-off diameter of 2.8 cm should be operated. Mutations in exon 3, especially of codons 161/167 are at enhanced risk for metastatic PanNETs. Survival is significantly longer in operated non-metastatic VHL-PanNETs.

Source: Endocrine-Related Cancer - July 16, 2018 Category: Endocrinology Authors: Krauss, T., Ferrara, A. M., Links, T. P., Wellner, U., Bancos, I., Kvachenyuk, A., Villar Gomez de las Heras, K., Yukina, M. Y., Petrov, R., Bullivant, G., von Duecker, L., Jadhav, S., Ploeckinger, U., Welin, S., Schalin-Jantti, C., Gimm, O., Pfeifer, M., Tags: Research Source Type: research