Multigenic Disease and Bilineal Inheritance in Dilated Cardiomyopathy Is Illustrated in Nonsegregating LMNA Pedigrees [Original Articles]

Conclusions:
Our data support DCM as a genetically heterogeneous disease with, at times, multigene causation. Although the frequency of DCM resulting from multigenic cause is uncertain, our data suggest it may be higher than previously anticipated.

Source: Circulation: Cardiovascular Genetics - July 16, 2018 Category: Cardiology Authors: Cowan, J. R., Kinnamon, D. D., Morales, A., Salyer, L., Nickerson, D. A., Hershberger, R. E. Tags: Genetics, Cardiomyopathy, Heart Failure Original Articles Source Type: research