The influence of 5-aminolevulinic photodynamic therapy on colon cancer cells interleukins secretion in hypoxia-like condition in vitro
The biggest problem in cancer treatment is the recurrence of cancer associated with the presence of residual cancer cells, which leads to the progression of tumor growth and metastasis. Photodynamic therapy (PDT) efficaciously destroys cancer tissue, although can also induce a complex immune response, that potentiates antitumor immunity, what could be a chance to exterminate the residuals cancer cells [1]. Three cytokines, including IL-6, IL-8 and IL-10, play an crucial role in cancer progression and human anticancer defense, and the question is, how is its secretion by residual colon cancer cells during photodynamic therapy.
Source: Photodiagnosis and Photodynamic Therapy - Category: Laser Surgery Authors: Aleksandra Kawczyk-Krupka, Wojciech Latos, Piotr Ole ś, Zenon P. Czuba, Magdalena Latos, Magdalena Krupka, Huang Pengyun, Chuanshan Xu, Grzegorz Cieślar, Aleksander Sieroń Source Type: research