Porphyrins and Related Macrocycles: Combining photosensitization with radio- or optical-imaging for next generation theranostic agents

Herein this review intends to address several important questions, such as the nature of electromagnetic radiation and its use in photodynamic therapy, as well as the physical processes of photodynamic behaviour. A photosensitizer, for the purposes of this review, is a photoactive molecule that can serve as a therapeutic agent upon light activation, but can also be used as an imaging agent for diagnostics, thus combination of both these properties yields a theranostic agent [1]. The imaging component of these molecules can be obtained through optical properties or via radiolabelling of the photosensitizer [2].

Source: Photodiagnosis and Photodynamic Therapy - July 15, 2018 Category: Laser Surgery Authors: Jordon Sandland, Nela Malatesti, Ross Boyle Tags: Review Source Type: research