Variogram-based evaluations of DXA correlate with vertebral strength, but do not enhance the prediction compared to aBMD alone

Ancillary evaluation of spinal Dual-energy X-ray Absorptiometry (DXA) via variogram-based texture evaluation (e.g., Trabecular Bone Score) is used for improving the fracture risk assessment, despite no proven relationship with vertebral strength. The purpose of this study was thus to determine whether classical variogram-based parameters (sill variance and correlation length) evaluated from simulated DXA scans could help predicting the in vitro vertebral strength.Experimental data of thirteen human full vertebrae (i.e., with posterior elements) and twelve vertebral bodies were obtained from two existing studies.
Source: Journal of Biomechanics - Category: Biomedical Science Authors: Tags: Short communication Source Type: research