Hamartomatous polyposis syndromes: diagnosis and management
Hamartomatous polyps of the gastrointestinal tract are one of the major clinical features for several hereditary syndromes. Juvenile polyposis syndrome, Peutz-Jeghers syndrome, and PTEN hamartoma syndrome are inherited in an autosomal dominant fashion and predispose to formation of such polyps, especially in the colon and rectum. These polyps can lead to increased colorectal cancer risk and therefore should be managed with appropriate surveillance and treatment. In this article, the presentation, colorectal surveillance, and management of the three major hereditary hamartomatous syndromes is discussed.
Source: Seminars in Colon and Rectal Surgery - Category: Gastroenterology Authors: Molly M. Ford Source Type: research
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