Co-occurrence of mcr-3 and blaNDM-5 genes in multidrug-resistant ST709 Klebsiella pneumoniae from commercial chicken farm in China

In this study, a colistin- and carbapenem-resistant Klebsiella pneumoniae strain of sequence type 709 (ST709) recovered from commercial chicken farm in China was found to carry plasmid-borne colistin-resistant genes mcr-3.11 and a carbapenemase gene blaNDM-5. Whole-genome sequencing revealed that MYKLB95 strain contains 36 antibiotic resistance genes in its genome, gene mcr-3.11 was bracketed by two copies of the insertion sequence ISKpn40 on a 99-kb plasmid and blaNDM-5 was carried by a separate 46-kp IncX3 plasmid.
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Tags: Letter to the Editor Source Type: research