Peripheral interleukin-6 levels and working memory in nonobese adults: a post-hoc analysis from calerie study

Accumulating evidence indicates that a high content of sugar and fat in the diet may negatively impact cognitive function [27]. Although there are multiple explanatory variables, one leading candidate is the disturbances in inflammatory mediators [23]. There are substantial findings supporting the involvement of inflammatory cytokines in reductions of adaptive neuroplasticity in healthy individuals, where multiple studies implicate IL-6 as the most replicated pro-inflammatory alteration [24, 45].

Source: Nutrition - July 12, 2018 Category: Nutrition Authors: Alisson P. Trevizol, Elisa Brietzke, Ruth Bartelli Grigolon, Mehala Subramaniapillai, Roger S. McIntyre, Rodrigo B. Mansur Source Type: research