Amino acids profile after oral nutritional supplementation in hemodialysis patients with protein energy wasting

Some studies have shown abnormalities of nutritional status in patients with chronic kidney disease (CKD) [1,2]. Protein energy wasting (PEW) is highly prevalent in haemodialysis (HD) patients [3,4]. The underlying mechanisms of PEW are complex, but metabolic derangements related both to exaggerated protein degradation and decreased protein synthesis are of utmost importance [5,6,7,8]. Homeostasis between protein synthesis and degradation depends on protein intake and utilization. Accelerated protein degradation, without a sufficient protein supply, may lead to skeletal muscle wasting (9).

Source: Nutrition - July 12, 2018 Category: Nutrition Authors: Sylwia Ma łgorzewicz, Grażyna Gałęzowska, Monika Cieszyńska-Semenowicz, Joanna Ratajczyk, Lidia Wolska, Przemysław Rutkowski, Magdalena Jankowska, Bolesław Rutkowski, Alicja Dębska- Ślizień Source Type: research