History of Suicide Attempt and Right Superior Temporal Gyrus Volume in Youth with Treatment-Resistant Major Depressive Disorder

Suicide is the second leading cause of death in 15-29 year olds worldwide (WHO, 2016), and major depressive disorder (MDD) is a main risk factor for suicide. Presently, suicide risk assessment is limited, relying on patient self-reports and subjective judgement by clinical professionals. By comparison, neural structural differences may provide more objective markers of suicidality and are often more accessible than measures of brain function. An objective, biological model of suicidality would identify those at risk (Sudol and Mann, 2017) and provide targets for future neurobiologically-informed interventions.
Source: Journal of Affective Disorders - Category: Neurology Authors: Source Type: research