Olfactory deficits and psychosis-spectrum symptoms in 22q11.2 deletion syndrome

Olfactory functioning is a promising biomarker for psychosis in 22q11.2 deletion syndrome (22q11DS) but has not been well studied to date. This is a pilot effort to evaluate the potential for tests of olfactory functioning to contribute to risk and resilience prediction in 22q11DS, and is the first study to evaluate relationships among olfactory deficits, cognition and psychosis-spectrum symptoms. Odor identification and discrimination were evaluated in 32 individuals with 22q11DS and 110 healthy comparison subjects (HC).

Source: Schizophrenia Research - July 11, 2018 Category: Psychiatry Authors: Sunny X. Tang, Paul J. Moberg, James J. Yi, Andrew S. Wiemken, Erich M. Dress, Tyler M. Moore, Monica E. Calkins, Donna M. McDonald-McGinn, Elaine H. Zackai, Beverly S. Emanuel, Ruben C. Gur, Raquel E. Gur, Bruce I. Turetsky Source Type: research