Gene Therapy and Virotherapy of Gliomas.

Gene Therapy and Virotherapy of Gliomas. Prog Neurol Surg. 2018;32:112-123 Authors: Kim JW, Chang AL, Kane JR, Young JS, Qiao J, Lesniak MS Abstract Despite many recent advances in the management of gliomas, such as aggressive surgical resection, chemoradiotherapy, antiangiogenic therapy, and molecular targeted therapy, the survival of patients with high-grade neoplasms remains dismal. Gene therapy and oncolytic virotherapy have emerged as highly promising strategies for treatment of malignant brain tumors due to recent progress in understanding of the underlying cancer biology as well as improved techniques for genetic modification of potential therapeutics. PMID: 29990979 [PubMed - in process]
Source: Progress in Neurological Surgery - Category: Neurosurgery Tags: Prog Neurol Surg Source Type: research