Ultra-sensitive electrochemical sensing of acetaminophen and codeine in biological fluids using CuO/CuFe2O4 nanoparticles as a novel electrocatalyst

Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Foroozan Hasanpour, Masoumeh Taei, Somayeh TahmasebiAbstractCopper ferrite−copper oxide (CuO-CuFe2O4) nanoparticles as a semiconductor composite with p–n junction were synthesized by co-precipitation reaction. Then, a novel CuO-CuFe2O4 carbon paste modified electrode was fabricated which displays an effectual electrocatalytic response to the oxidation of acetaminophen (AC) and codeine (CO). A linear range of 0.01–1.5 μmol L−1 and 0.06–10.0 μmol L−1 with the detection limits of 0.007 μmol L−1 and 0.01 μmol L−1 were achieved for AC and CO, respectively. The practical usage of the proposed sensor revealed reasonable results for quantification of AC and CO in biological fluids.Graphical abstract
Source: Journal of Food and Drug Analysis - Category: Food Science Source Type: research