Estimated versus achieved maximal oxygen consumption in severely burned children maximal oxygen consumption in burned children

Severe burns affect multiple organ systems and result in a loss of muscle mass, increased cardiac work, and protein catabolism [1 –4]. We have previously shown patients also experience decreased cardiorespiratory exercise capacity for up to 2 years after burn [5]. Pharmacological treatments are sometimes used to counteract increased cardiac work. One such treatment is the administration of propranolol, a nonselective β-adre nergic receptor antagonist, which can reduce cardiac work and burn-induced hypermetabolism [1].

Source: Burns : Journal of the International Society for Burn Injuries - July 10, 2018 Category: Cosmetic Surgery Authors: Christian Tapking, Daniel Popp, David N. Herndon, Ludwik K. Branski, Ronald P. Mlcak, Oscar E. Suman Source Type: research