Increased glomerular Bax/Bcl2 ratio is positively correlated with glomerular sclerosis in lupus nephritis

ConclusionThe intrinsic pathway of apoptosis interfere in the pathogenesis of lupus glomerulonephritis. The balance between bax and bcl2 proteins might have a role in regulating the progression of glomeruli from proliferative to sclerotic state.
Source: Pathophysiology - Category: Pathology Source Type: research