Mechanism underlying bergapten-mediated regulation of vincristine transport in MDCK-MDR1 cells

ConclusionsOverall, we concluded that the possible mechanism through which bergapten inhibits vincristine transport was related to the bergapten-mediated upregulation of P-gp protein and mRNA expression, membrane fluidity or P-gp enzyme activity.
Source: Chinese Herbal Medicines - Category: Complementary Medicine Source Type: research