Late recurrence of fulminant myocarditis related to HSS/DRESS

Publication date: Available online 1 February 2018Source: Cor et VasaAuthor(s): Miguel Ardérius, Miguel Nobre Menezes, Tiago Marques, Dulce Brito, Ana Ortins-Pina, Mónica Mendes Pedro, Fausto Pinto, Fátima VeigaAbstractHypersensitivity Syndrome or Drug Reaction with Eosinophilia and Systemic Symptoms (HSS/DRESS) is a rare pharmacological hypersensitivity reaction that may include cardiac involvement, with high mortality and long-term heart failure.A 28-year-old woman, two months after the diagnosis of DRESS secondary to sulfasalazine, developed fulminant eosinophilic necrotizing myocarditis. After intensive multiorgan support, recovery and cardiac function normalization were observed. Eight months later presented a recurrence with fast progression to refractory cardiogenic shock and death.We alert to a rare and underdiagnosed pathology, with adverse prognosis, needing timely identification and treatment.
Source: Cor et Vasa - Category: Cardiology Source Type: research