Perioperative Implications of Common and Newer Psychotropic Medications Used in Clinical Practice

Publication date: Available online 2 July 2018Source: Best Practice & Research Clinical AnaesthesiologyAuthor(s): Alan D. Kaye, Ryan J. Kline, Elliott R. Thompson, Aaron J. Kaye, Justin A. Terracciano, Harish B. Siddaiah, Richard D. Urman, Elyse M. CornettAbstractPsychotropic medications are widely prescribed by clinicians as both primary therapy for a variety of psychiatric and neurodegenerative diseases and as adjunctive analgesics for use in the perioperative period. It is critical to understand various modes of action, drug-drug interactions, side effects, and clinical implications. Health care providers must understand how these medications interact with anesthetics, as well as other drugs used in perioperative care. This manuscript, therefore, provides a review regarding psychiatric and neurodegenerative diseases, psychotropic medications used to treat them, and how they affect anesthesia and perioperative care. We will also discuss new, emerging drugs, and challenges they may cause during the perioperative period. Future direction of investigation into the role of these drugs during the perioperative period and implications is also discussed.
Source: Best Practice and Research Clinical Anaesthesiology - Category: Anesthesiology Source Type: research